当然,风险亦不容忽视。Infigratinib是泛FGFR1-4抑制剂,对FGFR1等的抑制可能引起高磷血症等副作用。3期试验中约有4%患者出现轻度、短暂的高磷血症。在儿科长期用药的背景下,其安全性仍需更严格的监测,监管的要求也会更严格。
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NASA wrote a statement saying that the astronaut experienced an unknown medical event on January 7 "that required immediate attention" from his fellow crew members. Fincke added that his "status quickly stabilized" thanks to the "quick response and the guidance" of the flight surgeons.
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